Saturday, February 23, 2019

Inbrija




So, what is this Inbrija everyone is taking about? I am so very glad that you asked! It is a medication (levodopa in an inhaler) for off periods. I will try to simplify this with a personal explanation. I take my medication (carbidopa/levodopa) at 6am, 12noon and 6pm and my off periods are roughly 11am to 1pm and 5pm to 7pm. Essentially, off periods are when the effects of one dose is wearing off and the next dose has not taken effect. At these times, my hands move slower, my voice fluctuates and my right leg drags as my right foot turns out.  Hopefully, Inbrija will help!

Why did the development of such a drug take so long? The answer to this question is long and complicated. Essentially, it is because there is no profit in it. Wow, that was neither long nor complicated! The reason for this is the patent is up on carbidopa/levodopa and it is available in generic form. Pharmaceutical companies spend millions of dollars developing and testing new drugs in exchange for a patent that gives them a period of exclusivity. (Side Note: Parkinson’s effects roughly 1 in every 100 people and therefore, carbidopa/levodopa is on the Word Heath Organizations’ list of essential medications.)

So how did this get developed? Simple, the Michael J Fox foundation paid for it to be developed! The Michael J Fox foundation provided Citiva now Acorda with two grants totaling $1.3 million

"...Inbrija exists only because of the efforts of the Michael J. Fox Foundation, which Fox founded in 2000. What's more, it's the first drug to be approved for treatment in which the Fox Foundation played a significant role in both the approach and the funding." (Allison Boiles, Bloomberg, January 23, 2019)

This man and his foundation are amazing! 

"In its 18 years, the foundation has raised -- and spent -- over $800 million. The scientists who have received Fox Foundation funding have made serious advances toward understanding what causes Parkinson's. Once a research backwater, Parkinson's research is now something scientists are eager to be involved in, thanks to the foundation. The Fox Foundation has become the fulcrum on which Parkinson's research pivots."  (Allison Boiles, Bloomberg, January 23, 2019)

Another post is coming soon. Thank you for reading!


3 comments:

  1. i was diagnosed of parkinson disease 5 years ago,i started azilect,then mirapex as the disease progressed in february last year,and i started on parkinson disease Herbal medicine from ultimate herbal home,few months into the treatment i made a significant recovery,almost all my symptoms are gone,great improvement with my movement and balance,it been a year and life has been so good for me,contact them at ultimatehealthhome@gmail.com

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  3. my dad was diagnosed with Parkinson’s disease.his symptoms were shuffling of feet,slurred speech,degradation of hand writing, horrible driving skills, right arm held at 46 degree angle, things were tough for me, but now he finally free from the disease with the help of total cure from ULTIMATE LIFE CLINIC, he now walks properly and all symptoms has reversed, he was having trouble with balance especially at night, getting into the shower and exiting it is difficult,getting into bed is also another thing he finds impossible.we had to find a better solution for his condition which really helped him a lot,the biggest helped we had was ultimate life clinic they walked us through the proper steps,i recommended this www.ultimatelifeclinic.com to anyone who also needs help.

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